The Microbiome – A Complex Biocenosis
The human microbiome is a highly complex biocenosis. Up to 100 trillion bacteria populate a single person. The vast majority of these live in the intestines.
This means that we consist of 100 times more bacteria than body cells. All these microorganisms are in a regulated exchange with each other and together form the biocenosis. Therefore, microbiome bacteria should never be considered in isolation, but always in a holistic context.
The vast majority of these bacteria cannot be detected with conventional methods such as cultivation. It is estimated that up to 99% of bacteria present in the human body are non-cultivable.
We support companies in microbiome research with professional know-how and innovative products, technologies and problem solutions.
FISH technology is described in the European Pharmacopoeia in chapter 5.1.6. Using this method enables a specific identification and quantification of living microorganisms directly in the sample material. With VIT® gene probe technology, we have developed an industrial standard of FISH.
We work with a large technology portfolio consisting of FISH, Flow VIT® and other powerful and alternative methods in order to apply the best possible approach for your task.
With decades of experience in the field of biocenoses, direct microbiology and complex samples, vermicon has the know-how to find the appropriate solutions for you. Get in touch with us and describe your problem.
"The importance of bacteria for our health is becoming increasingly obvious. Probiotic drugs open up new avenues in the fight against civilization diseases such as allergies, respiratory diseases and gastrointestinal diseases. With this in mind, SymbioPharm GmbH is committed to consistently and continuously expanding all activities from research to the finished product, searching for new ways and finding unusual treatments.
For more than two decades, vermicon AG has been our accompanying, reliable partner in the research development and quality assurance of our products. With their innovative methods, microbiological know-how and professional way of working, we have found exactly the partner that complements us. The fast exchange with our direct contact person and the entire team in mutual trust is the guarantee for an uncomplicated and successful cooperation."
Dr. Kurt Zimmermann, Chief Security Officer (CSO), SymbioPharm GmbH
The Importance of the Microbiome
Current research shows that the importance of the microbiome has been seriously underestimated in recent decades. Actually, the bacteria do not only seem to have an impact on digestive processes, but also have a significant effect on many areas of health. Exciting results from research demonstrate that the psyche, for example, is also massively influenced by the microbiome.
The Human Body
The previous definition of a human organism as consisting of the totality of all body cells has been severely shaken. This is due to the fact that microorganisms with their vast gene pool are increasingly leading to a blurring of the previous, very clear boundaries. Until now, we used to talk about the human body as colonized by bacteria. Now the boundaries will have to be redefined as the human body does not only contain body cells but also microorganisms. Consequently, a human being is going to be defined as the totality of its body cells and of its bacteria. This is hardly surprising when one considers that, according to the endosymbiont theory, each body cell is the result of a fusion of eukaryotes and prokaryotes, in which bacteria in their role as mitochondria are responsible for the essential function of cell respiration.
Non-cultivable bacteria constitute the predominant majority of microorganisms in the microbiome and can be analyzed most effectively by using methods of direct microbiology. With this approach, no cultivation is performed. The microbial cell remains intact and can thus be identified and quantified.